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Open Trials

Gastrointestinal

RTOG 0436 - A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation for Patients with Esophageal Cancer who are treated without surgery

Prostate

RTOG 0815 - A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy with or without Short- Term Androgen Deprivation Therapy for Patients with Intermediate-Risk Prostate Cancer

Lung

ECOG 1505 - A Phase III Randomized Trial of Adjuvant Chemotherapy with or without Bevacizumab for Patients with Completely Resected Stage IB-IIIA NSCLC

ECOG 5508 - Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a Combination of Bevaciaumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced NSCLC

ACOSOG Z4099 - A Randomized Phase III Study of Sublobar Resection (+/- Brachytherapy) vs. Stereotactic Body Radiation Therapy in High Risk Patients with Stage I NSCLC (Approval still Pending)

Head/Neck

RTOG 0920 A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally Advanced Resected Head and Neck Cancer

Brain Metastases

RTOG 0933 A Phase II Trial of Hippocampal Avoidance during Whole Brain Radiotherapy for Brain Metastases

Breast

NSABP B 43 A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2+ Ductal Carcinoma In Situ Resected by Lumpectomy

CALGB 40601 Randomized Phase III Trial of Paclitaxel combined with Trastuzumab, Lapatinib, or Both as Neoadjuvant Treatment of Her2+ Primary Breast Cancer

Non-Therapeutic

Precision Therapuetic PT-207 Precision Therapeutic Registry Chemoresponse Assay in Solid Tumors

Diagnostic

ACRIN (American College of Radiology Imaging Network) NOPR Trial - Sodium Floride Bone Mets

ACRIN (American College of Radiology Imaging Network) NOPR Trial - The National Oncologic PET Registry—Center for Medicare and Medicaid Services to expand coverage for PET emission tomography to include cancer indications not currently covered

Research Coordinator:

Mary Lynn Haynes RN, OCN Telephone: (814) 838-0448

More detailed information about any specific trial may be available on the cooperative group website:

• RTOG - Radiation Therapy Oncology Group
• NSABP - National Surgical Adjuvant Breast and Bowel Project
• CTSU - Cancer Trials Support Unit
• ECOG - Eastern Cooperative Oncology Group