Regional Cancer Center ~ Erie, PA

Open Trials

Breast

CompLEEment- An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEED11) in combination with letrozole for the treatment of men and pre/postmenopausal women with HR+, HER2-negative advanced breast cancer with no prior hormonal therapy for advanced disease

E1Z11 - A Cohort Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS)

NSABP B51 - A randomized Phase III Clinical Trial evaluating post-mastectomy chest wall and Regional Nodal XRT and post-lumpectomy Regional Nodal XRT in patients with positive axillary nodes before Neoadjuvant chemotherapy who convert to pathologically negative axillary nodes after Neodjuvant chemotherapy.

EA1131 - A Randomized Phase III Post-Operative Trial of Platinum Based Chemotherapy Vs. Observation in Patients with Residual Triple-Negative Basal-Like Breast Cancer following Neoadjuvant Chemotherapy

ADVANCE SPI-GCF-301 - RAnDomized Trial of SPI-2012 Versus Pegfilgrastim in the Management of Chemotherapy Induced Neutropenia in Breast CANCEr Patients Receiving Docetaxel and Cyclophosphamide (ADVANCE)

SPI-POZ-201 - Study of Poziotinib in Patients With HER2-Positive Metastatic Breast Cancer

S1416- Phase II Randomized Placebo-Controlled Trial of Cisplatin with or Without ABT-888 (Veliparib) in Metastatic Triple-Negative Breast Cancer and/or BRCA Mutation-Associated Breast Cancer


Gastrointestinal

UPCI 13-074 - Randomized Phase II trial of Pre-Operative Gemcitabine and nab Paclitaxel with or without Hydroxychloroquine

PROSPECT/N1048: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients with Locally Advanced Rectal Cancer Undergoing Surgery


Lung

Alchemist- Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery

Celgene NSCL-003 - A Phase III, Randomized, Open-Label, Crossover, Multi-Center, Safety and Efficacy Study to evaluate NAB-PACLITAXEL (ABRAXANE®) as maintenance treatment after induction with NAB-PACLITAXEL plus Carboplatin in subjects with Squamous Cell Non-Small Cell Lung Cancer (NSCLC)

GO 29437 - A Phase III Study of MPDL3280A (Anti-PD-L1) in Combination With Carboplatin + Paclitaxel or Carboplatin + Nab-paclitaxel Compared With Carboplatin + Nab-paclitaxel in Patients With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC)


Lymphoma

CA209-655- Hodgkin Lymphoma Molecular Profiling and Clinical Outcomes in U.S. Community Oncology Practices


Melanoma

OPTIMIZE - Study in Patients with Unresectable and Metastatic Melanoma: The Optimize Study (An Observational Study)

S1404: High-Dose Recombinant Interferon Alfa-2B, Ipilimumab, or Pembrolizumab in Testing Patients with Stage III-IV High Risk Melanoma That Has Been Removed by Surgery


Multi-Site

UPCI 10-027 - Phase II Study for Curative Intent Treatment for Patients Presenting with Oligometastatic Disease

UPCI 10-028 - Phase II Study of Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy for patients with Oligo-recurrent Disease

EAY131 - NCI-MATCH - Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors or Lymphomas

My Pathway - A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf, and Erivedge Treatment Targeted Against Certain Mutations in Cancer Patients


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