Regional Cancer Center ~ Erie, PA

BRCA Analysis

Could you be at risk for hereditary breast and ovarian cancer?

Do you have a personal or family history of any of the following cancers?

  • Breast Cancer
  • Ovarian Cancer
  • Male Breast Cancer
  • Pancreatic Cancer
  • Prostate Cancer

You can inherit a broken gene, also known as a gene mutation, from either your mother or your father. Gene mutations in either your BRCA 1 or BRCA 2 genes make it much more likely that you may develop certain types of cancer:

  • Breast Cancer: up to 87%
  • Ovarian Cancer: up to 40%
  • Male Breast Cancer: up to 6.8%
  • Secondary Primary Breast Cancer: up to 64%
  • Pancreatic Cancer: up to 7%
  • Prostate Cancer: up to 15%

Take Control

The good news is you can do something about it.

There is a genetic test that you can talk to your doctor about today that will let you know if you have a broken BRCA 1 or BRCA 2 gene. This is also knows as Hereditary Breast and Ovarian Cancer Syndrome.

Enhanced Screening

  • Enhanced screening may increase the chance of detecting breast cancer at an early stage, when it may have a better chance of being treated successfully.
  • Some women who test positive for BRCA 1 and BRCA 2 mutations may choose to start screening at younger ages than the general population or have more frequent screening. Some experts recommend that women who carry a harmful BRCA 1 or BRCA 2 mutation undergo clinical breast examinations and/or mammograms every year, beginning at age 25 to 35 years.
  • No effective methods of ovarian cancer screening currently exist.
  • The benefits of screening for breast and other cancers in men who carry harmful mutations in BRCA 1 or BRCA 2 is also not known, but some expert groups recommend that men who are known to carry a harmful mutation undergo regular mammography as well as testing for prostate cancer.

Is BRCA1 and BRCA2 Genetic Testing Appropriate for You?

Genetic testing may be appropriate if you have a personal history and/or family history of any of the following:

  • Breast cancer diagnosed at age 45 or younger
  • Triple negative breast cancer diagnosed age 60 or younger
  • Bilateral breast cancer (breast cancer in both breasts)
  • Ovarian, fallopian tube, or primary peritoneal cancer at any age
  • Ashkenazi Jewish ancestry with breast cancer at any age
  • Male breast cancer at any age
  • Three or more cases of breast, ovarian, pancreatic, and/or prostate cancer (on the same side of the family)
  • Known BRCA1 or BRCA2 mutation in the family

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